Paracetamol is one of the widely available medications and its poisoning is common across the world. N- acetyl cysteine (NAC) is being used as an antidote for the same. The conventional protocol for NAC is an infusion of 300mg/Kg over 21 hours. The downfall of this regimen is because of the higher incidence of dose…
Classification Type II pyrethroids have an alpha-cyano moiety (but features of cyanide poisoning have not been reported) Mechanism of action In vitro, pyrethroids have an effect on Type I pyrethroids – produce repetitive discharges (burst discharges) for a single stimulus Type II pyrethroids – prolongs the period of depolarization Pyrethroids often contain additives like piperonyl…
Definition of hypertension Hypertensive Crisis Causes Investigations Treatment goals References ◦ Rajeev Gupta, Venkata Ram. Hypertension Epidemiology in India: Emerging aspects. Curr opin cardiol. 2019Jul;34(4):331-341. ◦ Jayanthi Chandar, Gastón Zilleruelo. Hypertensive crisis in children. Pediatr Nephrol. (2012) 27:741–75. ◦ 2020 International Society of Hypertension Global Hypertension Practice Guidelines ◦ Tintinallis emergency medicine, a comprehensive study…
The higher the HEAVEN criteria, the lower the likelihood of achieving first pass intubation success, overall intubation success, and first attempt intubation success without desaturation.
Preparations Contraindications Multiple Dose activated charcoal Indications Contraindications Any Contraindication for single dose activated charcoal Dosing
Neonicotinoids are newer insecticides which are less toxic to humans compared to organophosphates. This group of insecticides are neurotoxic and specifically acts on nicotinic Acetylcholine receptors in central nervous system. EPA has classified neonicotinoids as class II and class III toxins. Even though used widely in the field of horticulture, these compounds are found to…
Corticosteroids are dual edged sword in medicine. Physicians prescribe corticosteroids to patients with viral infections to life threatening ARDS. The side effects are often neglected but cause significant reduction in quality of life of the patient. The last update of use of corticosteroid use in critical care medicine was in 2017. With the availability of…
Case: 69yr old female presented to ER with h/o 1 episode of vomiting and generalized weakness for 1 hour. Bystanders also gave h/o itching all over the body after vomiting. While the patient was being shifted to bed from wheelchair to bed she developed up-rolling of eyes and stiffening of her limbs. She was connected…
M.A.R.C.H mnemonic is used for prehospital assessment and stabilization of trauma victims. It was initially proposed in the military, for assessing injured soldiers. Components of M.A.R.C.H protocol
LTOWB is derived from a donor of o group, and it has low levels of titres of anti a and anti b (IgM <250.4). It has been used widely for resuscitating hemorrhagic shock secondary to massive trauma. Shelf life is 21 days with citrate phosphate dextrose (CPD) and 35days with citrate phosphate dextrose adenine (CPDA-1)…